Электросудорожная терапия. ЗАКЛЮЧЕНИЕ
Электросудорожная терапия Антипсихотические препараты давно заменили инсулиношоковое лечение и электросудорожную терапию при лечении шизофрении. В нескольких исследованиях, однако, показано, что по своей эффективности электросудорожная терапия не уступает антипсихотическим препаратам [85]. Некоторые практические врачи предпочитают назначать определенным категориям больных шизофренией одновременно антипсихотические препараты и электросудорожную терапию. В одном из контролированных испытаний было продемонстрировано, что со-четанное назначение фенотиазиновых препаратов и электросудорожной терапии привело к более быстрому формированию ремиссии, чем в случае самостоятельного применения фенотиазиновых средств [86]. Широко известен положительный клинический опыт применения электросудорожной терапии при состояниях кататонического возбуждения или негативизма, а также при других тяжелых, угрожающих жизни больного психотических состояниях. В одном из недавно опубликованных сообщений отмечен на положительный эффект электросудорожной терапии в комбинации с клозапином у больных с недостаточной реакцией на проводимую стандартную терапию [87]. ЗАКЛЮЧЕНИЕ На рис. 5. 5 показана тактика лечения острых психотических состояний с возможными альтернативными подходами в случае недостаточной терапевтической реакции или возникновения осложнений в виде кататонических расстройств, агрессивности или аффективных нарушений. литература 1. McCarthy RH, Terkelsen KG. Rdsperidone augmentation of clozapine. Pharmacophsychiatry 1995; 28: 61-63. 2. Dubin WR. Rapid tranquilization: antipsychotic or benzodiazepine. J Clin Psychiatry 1988; 49 (12): 5-11. 3. Casey DE. Tardive dyskinesia. In: Meltzer HY, ed. Psychopharmacology, the third generation of progress. New York: Raven Press, 1987: 1411-1419.
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