Главная | Обратная связь | Поможем написать вашу работу!
МегаЛекции

Электросудорожная терапия. ЗАКЛЮЧЕНИЕ




Электросудорожная терапия

Антипсихотические препараты давно заменили инсулиношоковое лечение и электросудорож­ную терапию при лечении шизофрении. В не­скольких исследованиях, однако, показано, что по своей эффективности электросудорожная терапия не уступает антипсихотическим пре­паратам [85]. Некоторые практические врачи предпочитают назначать определенным катего­риям больных шизофренией одновременно ан­типсихотические препараты и электросудорож­ную терапию. В одном из контролированных испытаний было продемонстрировано, что со-четанное назначение фенотиазиновых препа­ратов и электросудорожной терапии привело к более быстрому формированию ремиссии, чем в случае самостоятельного применения фено­тиазиновых средств [86]. Широко известен по­ложительный клинический опыт применения электросудорожной терапии при состояниях кататонического возбуждения или негативизма, а также при других тяжелых, угрожающих жизни больного психотических состояниях. В одном из недавно опубликованных сообщений отме­чен на положительный эффект электросудо­рожной терапии в комбинации с клозапином у больных с недостаточной реакцией на прово­димую стандартную терапию [87].

ЗАКЛЮЧЕНИЕ

На рис. 5. 5 показана тактика лечения острых психотических состояний с возможными аль­тернативными подходами в случае недостаточ­ной терапевтической реакции или возникнове­ния осложнений в виде кататонических рас­стройств, агрессивности или аффективных нарушений.

литература

1. McCarthy RH, Terkelsen KG. Rdsperidone aug­mentation of clozapine. Pharmacophsychiatry 1995; 28: 61-63.

2. Dubin WR. Rapid tranquilization: antipsychotic or benzodiazepine. J Clin Psychiatry 1988; 49 (12): 5-11.

3. Casey DE. Tardive dyskinesia. In: Meltzer HY, ed. Psychopharmacology, the third generation of progress. New York: Raven Press, 1987: 1411-1419.

4. Fornum F. Biochemistry, anatomy, and pharma­cology of GABA neurons. In: Meltzer HY, ed. Psychopharmacology: the third generation of progress. New Yorfc Raven Press, 1987: 173-182.

5. Garbutt J, VanKammen DPO. The interactions between GABA and dopamine: implications for schizophrenia. Schizophr Bull 1983; 9(3): 336-353.

6. Lloyd KG, Murselli PL. Psychopharmacology of GABAergic drugs. In: Meltzer HY, ed. Psycho-pharmacology: the third generation of progress. New York: Raven Press, 1987: 183-195.

7. Meldrum B. Pharmacology of GABA. Clin Neu-ropharmacol 1982; 5 (3): 293-316.

8. Mohler IJ, Evans SJ. γ -Aminobutyric acid (GABA), receptors and their association with benzodia-zepine recognition sites. In: Meltzer HY, ed. Psy­chopharmacology: the third generation of progress. New York: Raven Press 1987: 265-272.

9. CsernanskyJG, Lombrozo L, Gulevich GD, Hoi-lister LE. Treatment of negative schizophrenic symptoms with alprazolam: a preliminary open-label study. J Clin Psychopharmacol 1984; 4 (6): 349-352.

10. Douyon R, Angrist B, Peselow E, Cooper T, Rot-rosen J. Neuroleptic augmentation with alpra­zolam: clinical effects and pharmacokinetic correlates, Am J Psychiatry 1989; 146 (2): 231-234.

11. Nestoros JN, Nair NPV, Pulman JR, Schwartz G, Bloom D. High doses of diazepam improve neu-roleptic-resistant chronic schizophrenic pati­ents. Psychopharmacology 1983; 81: 42-47.

12. Weizman A, Tyano S, Wijsenbeek H, Ben DM. High dose diazepam treatment and its effect on prolactin secretion in adolescent schizophrenic patients. Psychopharmacology 1984; 82: 382-385.

13. Wolkowitz OM, Breier A, Doran A, et al. Alpra­zolam augmentation of the antipsychotic ef­fects of fluphenazine in schizophrenic patients. Arch Gen Psychiatry 1988; 45: 664-671.

14. Csernansky JG, Riney SJ, Lombrozo L, Ove­rall JE, Hollister LE. Double-blind comparison of alprazolam, diazepam, and placebo for the treatment of negative schizophrenic symptoms. Arch Gen Psychiatry 1988; 45: 655-659.

15. Holden JMC, Itil TM, Keskiner A, et al. Thiori-dazine and chlordiazepoxide, alone and com­bined, in the treatment of chronic schizophre­nia. Compr Psychiatry 1968; 9 (6): 633-643.

16. Hanlon ТЕ, Ota KY, Kurland AA. Comparative effects of fluphenazine, fluphenazine-chlor-diazepoxide and fluphenazine-imipramine. Dis NerySyst 1970; 31: 171-177.

17. Hanlon ТЕ, Ota KY, Agallianos DD, et al. Com­bined drug treatment of newly hospitalized acutely ill psychiatric patients. Dis Nerv Syst 1969: 30: 104-116.

18. Kellner R, Wilson RM, Muldawer MD, Pathak D. Anxiety in schizophrenia. · the responses to chlordiazepoxide in an intensive design study. Arch Gen Psychiatry 1975; 32: 1246-1254.

19. Lingjaerde 0. Effect of the benzodiazepine de­rivative estazolam in patients with auditory hal­lucinations: a multi-centre double-blind, cross-over study. Acta Psychiatr Scand 1982; 65: 339-354.

20. Ruskin P, Averburch I, Buchman RW, et al. Ben-zodiazepines in chronic schizophrenia. Biol Psychiatry 1979; 14 (3): 557-558.

21. Arana GW, Ornsteen ML, Kanter F, Friedman HL, Greenblatt DJ, Shader RL. The use of benzodia-zepines for psychotic disorders. A literature re­view and preliminary clinical findings. Psycho­pharmacol Bull 1986; 22 (1): 77-87.

22. Salam SA, Pillai A, Beresford TP. Lorazepam for psychogenic catatonia. Am J Psychiatry 1987; 144: 1082-1083.

23. Salam SA, Kilzich N. Lorazepam in psychogenic catatonia: an update. J Clin Psychiatry 1988; 49 (Suppl): 16-21.

24. Greenfeld D, Conrad C, Kincare P, Bowers MB Jr. Treatment of catatonia with low-dose lo-razepam. Am J Psychiatry 1987; 144: 1224-1225.

25. Walter-Ryan WG. Treatment for catatonic symp­toms with intramuscular lorazepam. J Clin Psy­chopharmacol 1985; 5: 123-124.

26. Wetzel H, Heuser I, Benker 0. Stupor and affec­tive state: alleviation of psychomotor distur­bances by lorazepam and recurrence of symp­toms with RO 15-1788. J Nerv Ment Dis 1987; 175: 240-242.

27. Martenyi F, Harangozo J, Laszlo M. Clonazepam for the treatment of catatonic schizophrenia. Am J Psychiatry 1989; 146: 1230.

28. McEvoy JP, Lohr JB. Diazepam for catatonia. Am J Psychiatry 1984; 141: 284-285.

29. Menza MA, Harris D. Benzodiazepines and ca­tatonia: an overview. Biol Psychiatry 1989; 26: 842-846.

30. Bodkin JA. Emerging uses for high-potency benzodiazepines in psychotic disorder. J Clin Psychiatry 1990; 5 (Suppl): 41-46.

31. Saltana AS, Kilzieh N. Lorazepam treatment of psychogenic catatonia: an update. J Clin Psy­chiatry 1988; 49 (12): 16-21.

32. Jimerson DC, Van Kammen DP, Post RM, Docherty JP, Bunney WE Jr. Diazepam in schizophrenia: a preliminary double-blind trial. Am J Psychiatry 1982; 139 (4): 489-491.

33. Cohen S, Khan A, Johnson S. Pharmacological management of manic psychosis in an un­locked setting. J Clin Psychopharmacol 1987; 7 (4): 261-264.

34. Hass S, Emrich HM, Beckmann H. Analgesic and euphoric effects of high dose diazepam in schizophrenia. Neuropsychobiology 1982; 8: 123-128.

35. Mondell JG. Further experience and observa­tions with lorazepam in the management of be­havioral agitation [Letter]. J Clin Psychophar­macol 1986; 6 (6): 385-387.

36. Salzman C. Use of benzodiazepines to control disruptive behavior in inpatients. J Clin Psychi­atry 1988; 49 (Suppl 12): 13-15.

37. Pato CN, Wolkowitz OM, Rapaport M, Schulz SC, Pickar D. Benzodiazepine augmentation of neu-roleptic treatment in patients with schizophre­nia. Psychopharmacol Bull 1989; 25 (2): 263-266.

38. Casey JF, Hollister LE, Klett CJ, Lasky JJ, Caf-fey GM. Combined drug therapy of chronic schizophrenics. Controlled evaluation of placebo, dextro-amphetamine, imipramine, isocarboxa-zid, and trifluoperazine added to maintenance doses of chlorpromazine. Am J Psychiatry 1961; 117: 997-1003.

39. Davis JM. The treatment of schizophrenia. Curr Opin Psychiatry 1990; 3: 29-34.

40. Weissman M. The psychological treatment of depression. Evidence for the efficacy of psycho therapy alone, in comparison with, and in com­bination with pharmacotherapy. Arch Gen Psychiatry 1979; 36: 1261-1269.

41. Goff DC, Brotman AW, Waites M, McCormick S. Trial of fluoxetine added to neuroleptics for treatment-resistant schizophrenic patients. Am J Psychiatry 1990; 147 (4): 492-494.

42. Goldman MB, Janecek HM. Adjunctive fluoxe­tine improves global function in schizophrenia. J Neuropsych Clin Neurosci 1990; 2: 429-431.

43. Bleich A, Brown S, Kann R, et al. The role of serotonin in schizophrenia. Schizophr Bull 1988; 14: 297-325.

44. Biederman J, Lerner Y, Belmaker RH. Combina­tion of lithium carbonate and haloperidol in schizo-affective disorder. A controlled study. Arch Gen Psychiatry 1979; 36: 327-333.

45. Okuma T, Yamashita I, Takahashi R, et al. A dou­ble-blind study of adjunctive carbamazepine versus placebo on excited states of schizo-• phrenic and schizoaffective disorders. Acta Psy-chiatr Scand 1989; 80: 250-259.

46. Altamura AL, Mauri MC, Mantero M, et al. Clo-nazepam/haloperidol combination therapy in schizophrenia: a double-blind study. Acta Psy-chiatr Scand 1987; 76: 702-706.

47. Smith ME. A clinical study of chlorpromazine and chlordiazepoxide. Conn Med 1961; 25: 153-157.

48. Hankoff LD, Rudorfer L, Paley HM. A reference study of ataraxics: a two-week double blind outpatient evaluation. J New Drugs 1962; 2: 173-178.

49. Azima H, Arthurs D, Silver A. The effects of chlordiazepoxide (Librium) in anxiety states. Can Psychiatr Assoc J 1962; 7: 44-50.

50. Merlis S, Turner WJ, Krumholz W. A double-blind comparison of diazepam, chlordiazepoxi­de and chlorpromazine in psychotic patients. J Neuropsychiatry 1962; 3 (Suppl): S133-S138.

51. Rao AV. A controlled trial with " Valium" in some psychiatric disorders. Indian J Psychiatry 1964; 4: 188-192.

52. Maculans GA. Comparison of diazepam, chlor-prothixene and chlorpromazine in chronic schizophrenic patients. Dis Nerv Sys 1964; 25: 164-168.

53. Stonehill E, Lee H, Ban ТА. A comparative study with benzodiazepines in chronic psychotic pa­tients. Dis Nerv Sys 1966; 27: 411-413.

54. Gundlach R, Engelhardt DM, Hankoff L, et al. A double-blind outpatient study of diazepam (Valium) and placebo. Psychopharmacologia 1966; 9: 81-92.

55. Michaux MH, Kurland AA, Agallianos DD. Chlor-promazine-chlordiazepoxide and chlorpro-mazine-imipramine treatment of newly hospi­talized, acutely ill psychiatric patients. Curr Ther Res 1966; 8 (Suppl): 117-152.

56. Hekimian LJ, Friedhoff AJ. A controlled study of placebo, chlordiazepoxide and chlorpro­mazine with thirty male schizophrenic patients. Dis Nerv Sys 1967; 28: 675-678.

57. Holden JMC, Itil TM, Keskiner A, et al. Thiori-dazine and chlordiazepoxide, alone and com­bined, in the treatment of chronic schizophre­nia. Compr Psychiatry 1968; 9: 633-634.

58. Guz L, Moraea R, Sartoretto JN. The therapeutic effects of lorazepam in psychotic patients tre­ated with haloperidol: a double-blind study. Curr Ther Res 1972; 14: 767-774.

59. Kellner R, Wilson RM, Muldawer MD, et al. Anxiety in schizophrenia: the responses to chlordiazepoxide in an intensive design study. Arch Gen Psychiatry 1975; 32: 1246-1254.

60. Ruskin P, Averbukh I, Belmaker RH, et al. Ben-zodiazepines in chronic schizophrenia. Biol Psychiatry 1979; 14: 557-558.

61. Marneros A. Anxiolytische zusatzbehandlung bei den affektbetonten schizophrenien. Thera-piewoche 1979; 29: 7533-7538.

62. Lingjaerde 0, Engstrand E, Ellingsen P, et al. Antipsychotic effect of diazepam when given in addition to neuroleptics in chronic psychotic patients: a double blind clinical trial. Curr Ther Res 1979; 26: 505-514.

63. Lerner Y, Lwow E, Levitin A, et al. Acute high-dose parenteral haloperidol treatment of psy­chosis. Am J Psychiatry 1979; 136: 1061-1064.

64. Nishikawa T, Tsuda A, Tanaka M, et al. Prophy­lactic effect of neuroleptics in symptom-free schizophrenics. Psychopharmacology 1982; 77: 301-304.

65. Nestoros JN, Suranyi-Cadotte BE, Specs RC, et al. Diasepam in high doses is effective in schizo­phrenia. Prog Neuropsychopharmacol Biol Psy­chiatry 1982; 6: 513-516.

66. Karson CN, Weinberger DR, Bigelow L, et al. Clonazepam treatment of chronic schizophre­nia: negative results in a double-blind, pla­cebo-controlled trial. Am J Psychiatry 1982; 139: 1627-1628.

67. Nestoros JN, Nair NPV, Pulman JR, et al. High doses of diazepam improve neuroleptic-resi-stant chronic schizophrenic patients. Psycho-pharmacology 1983; 81: 42-47.

68. Csernansky JG, Riney SJ, Lombrozo L, et al. Double-blind comparison of alprazolam, dia­zepam and placebo in the treatment of nega­tive schizophrenic symptoms. Arch Gen Psychi­atry 1988; 45: 655-659.

69. Wolkowitz OM, Breier A, Doran AR, et al. Al­prazolam augmentation of the antipsychotic effects of fluphenazine in schizophrenic pa­tients: preliminary results. Arch Gen Psychiatry 1988; 45: 664-671.

70. Wolkowitz OM, Pickar D. Benzodiazepines in the treatment of schizophrenia: a review and reappraisal. Am J Psychiatry 1991; 148: 714-726.

71. Dixon L, Weiden PJ, Frances AJ, et al. Alpra­zolam intolerance in stable schizophrenic outpa­tients. Psychopharmacol Bull 1989; 25: 213-214.

72. Bacher NM, Lewis HA, Field PB. Combined al­prazolam and neuroleptic drug in treating schizo­phrenia. Am J Psychiatry 1986; 143: 1311-1312.

73. Sassim N, Grohmann R. Adverse drug reactions with clozapine and simultaneous application of benzodiazepines. Pharmacopsychiatry 1988; 21: 306-307.

74: Shopsin B, Kirn SS, Gershon S. A controlled study of lithium vs. chlorpromazine in acute schizo­phrenics. BrJ Psychiatry 1971; 119: 435-440.

75. Hirschowitz J, Casper R, Garver DL, Chang S. Lithium response in good prognosis schizo­phrenia. Am J Psychiatry 1980; 137(8): 916-920.

76. Atsmon A, Blum I. Treatment of acute porphy-ria variegata with propranolol. Lancet 1970; 24; 196-197.

77. Atsmon A, Blum I. The discovery. In: Roberts E, Amacher P, eds. Propranolol and schizophrenia. New York: Alan Liss, 1978.

78. Atsmon A, Blum I, Steiner M, Latz A, Wijsen-beek H. Further studies with propranolol in psychotic patients. Psychopharmacologia 1972; 27: 249-254.

79. Atsmon A, Blum I, Wijsenbeek H, Maoz P, Stein­er M, Zielgeirnan G. The short-term effects of adrenergic-blocking agents in a small group of psychotic patients. Psychiatria Neurologia Neu-rochirurgia 1971; 74: 251-258.

80. Yorkston NJ, Zaki SA, Havard CWH. Propranolol in the treatment of schizophrenia: an uncon­trolled study with 55 adults. In: Roberts E, Amacher P, eds. Propranolol and schizophrenia. New York: Alan R. Liss, 1978.

81. Yorkston NJ, Zaki SA, Malik MKU, Morrison RC, Havard CWH. Propranolol in the control of schizophrenic symptoms. Br Med J 1974; 4: 633-635.

82. Yorkston NJ, Zaki SA, Themen J, Havard CWTL Propranolol to control schizophrenic symp­toms. Adv Clin Pharmacol 1976; 12: 91-104.

83. Yorkston NJ, Zaki SA, Themen J, Havard CWH. Safeguards in the treatment of schizophrenia with propranolol. Postgrad Med J 1976; 52 (Suppl 4): 175-180.

84. Davis JM, Janicak PG, Chang S, Klerman K. Re­cent advances in the pharmacologic treatment of the schizophrenic disorders. In: Grinspoon L, ed. Psychiatry 1982 annual review. Washington, DC: APPI, 1982.

85. Langsley DG, Enterline JD, Hickerson GX. A com­parison of chlorpromazine and EST in treatment of acute schizophrenic and manic re­actions. Arch Neurol Psychiat. 1959; 81: 384-391.

Smith K, Surphlis WRP, Gynther MD, Shimku-nas AM. ЕСТ and chlorpromazine compared in the treatment of schizophrenia. J Nerv Ment Dis 1967; 144: 284-290.

87. Benaton R, Sirota P, Megged S. Neuroleptic-resistant schizophrenia treated with clozapine and ЕСТ. Convuls Ther 1996; 12: 117-121.

 

Поделиться:





Воспользуйтесь поиском по сайту:



©2015 - 2024 megalektsii.ru Все авторские права принадлежат авторам лекционных материалов. Обратная связь с нами...