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5. Тестирование готового продукта 5.1. Безопасность
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5. Тестирование готового продукта 5. 1. Безопасность
5. 2. Иммуногенность
Необходимо проводить тест на отсутствие токсических или раздражающих характеристик (смотрите Раздел С. 4. 2. ).
Иммуногенность туберкулина необходимо оценивать биологическими методами. Эти методы необходимо использовать для HCSM и ППД туберкулинов; эти методы основаны на сравнении тестируемых туберкулинов со стандартным справочным препаратом туберкулина того же типа (см. Раздел С. 4. 4).
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NB:
Существуют Справочные лаборатории МЭБ по туберкулезу КРС (см. Таблицу в Части 4 данного Руководства по наземным животным или можно обратиться на сайт МЭБ и изучить последний список: http: //www. oie. int/en/our-scientific-expertise/reference-laboratories/list-of-laboratories/). Вы можете обратиться в референтные лаборатории МЭБ для получения дополнительной информации о диагностических тестах, реагентах и вакцинах от туберкулеза КРС.
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